Welcome to Angel City Research, Inc.

About Us

Who are we?

Angel City Research, is a multi-specialty medical group located in the heart of Los Angeles and specialized in clinical research of treatments for Diabetes and related disorders.  The research team is led by our Principal Investigator, Dr. Felix Sigal.  He is a dedicated clinician and thought leader with over 20 years of clinical experience. Under his direction, the Angel City Research team of physicians and staff explore cutting-edge treatments for the treatment of diabetes, and related disorders such as neuropathy, diabetic foot ulcers, venous leg ulcers, and non-healing wounds.


Felix Sigal, DPM, is an experienced clinical investigator, having conducted over 27 clinical research studies over the past decade. Dr. Sigal considers clinical research trials an essential part of the armamentarium to combat disease and raise the standard care for his expansive population of patients. 

Trusted Research Partner

Angel City Research is located adjacent to St.Vincent’s Medical Center, in the heart of one of the most densely populated areas of the second largest city (18 Million) in the United States, Los Angeles, CA.  Dr. Sigal is a recognized “go-to partner” for research efforts.  The site has is uniquely positioned to execute study plans, producing timely quality evaluable data and highly robust research volunteer recruitment.

Site Content

Scope of Research

Therapeutic Areas

We research treatments for all disorders suffered by diabetic patients, with a special interest in:

  • Diabetes Type 1
  • Diabetes Type 2
  • Diabetes complications
    • Diabetic foot ulcer
    • Venous leg ulcers
    • Diabetic nephropathy
    • Diabetic neuropathy
  • Metabolic Disorders (Obesity)
  • Hypertension
  • Onychomycosis
  • Bunion
  • Wound care

Principal Investigator

Dr. Sigal graduated from California State University of Northridge and California College of Podiatric Medicine. He then completed his Podiatric Residency training at LAC/USC General Hospital. After completing his surgical training, Dr. Sigal went into private practice in Los Angeles. His practice is focused on wound care, diabetic limb salvage and clinical research. Dr. Sigal is currently on staff at St. Vincent Medical Center and California Hospital Medical Center. Dr. Sigal resides in San Fernando Valley with his wife and his two children. In his free time, he enjoys fishing, boating, traveling and spending time with his family.

Mission Statement

The mission of Angel City Research, under the direction of our Principal Investigator, Dr. Felix Sigal, is to conduct clinical trials at our site with emphasis in Diabetes Type 1, Diabetes Type 2, and diabetes complications, executing robust recruitment of volunteer participants, timely collection and entry of data, ICH-GCP compliance, delivering evaluable data to our research partners and raising the standard of care for our patients by advancing treatment options. 

Staff Capabilities

  • All Staff are ICH/GCP/IATA Certified (bi-annually)
  • Site can use Central IRB
  • Bilingual Staff 
    • Spanish 
    • ASL
    • Russian
    • Nepalese
  • Site can translate ICF (Spanish)
  • This site is a dedicated clinical research group
  • We have a dedicated subject coordinator and backup coordinator
  • Site Study Coordinator has completed clinical trial for US regulatory submission


In today's fast paced world, communications technology has transformed our ability to stay in closer contact with our valued stake holders. We are committed to collaboration, transparency, and doing all that we can to accelerate access to better treatment options.   Subscribe below to receive news updates and other important information.

Should I Volunteer?

Deciding to participate in a clinical research study is an important decision.  Our friends at the Center for Information & Study on Clinical Research Participation (CISCRP) have very good resources to help you understand more about participation in clinical research.  Click on the link below to view more information.


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Contact Us

Drop us a line!

Better yet, see us in person!

We love our patients and research partners, so feel free to visit during normal business hours.

Angel City Research, Inc.

201 S Alvarado St,, Ste 819, Los Angeles, California 90057, United States

(213) 915-3171